Completed Pilot Projects InvestigatorAffiliationProject DatesProject TitleAckley, Brian D.KU Molecular Biosciences2018 - 2020On again, off again: Is pH a critical factor in pathogen killing?Berkland, CoryKU Molecular Biosciences2018 - 2019Modification of antibiotics to improve lung retention after inhalationBiswas, IndranilKUMC Microbiology, Molecular Genetics & Immunology2016 - 2018Developing Assays to Identify Inhibitors of Hfq of Acinetobacter BaumanniiBiswas, SaswatiKUMC Microbiology, Molecular Genetics & Immunology2021 - 2023Improve production and bioactivity of lantibiotic MU1140 for inhibition of gram-positive pathogensBloom, StevenKU Chemistry2020 - 2021Illuminating Old Catalysts for the Synthesis of Anti-Infective HIV PeptidesBose, JeffreyKUMC Microbiology, Molecular Genetics & Immunology2018 - 2019Biochemical Characterization and Immunological Consequence of MRSA Fatty Acid KinaseBoskovic, ZarkoKU Medicinal Chemistry2020 - 2022Synthetic chemistry elaboration of fragments targeting the bacterial type III secretionChandler, Josephine R.KU Molecular Biosciences2019 - 2020Chemical biology studies of malleilactone, a small-molecule toxin produced by Burkholderia pseudomalleiDavido, DavidKU Molecular Biosciences2016 - 2018The Chemical Biology of HSV Gene ExpressionDeeds, EricKU Molecular Biosciences2018 - 2019Novel Strategies for Proteasome Inhibition in Mycobacterium TuberculosisDeKosky, Brandon J.KU Pharmaceutical Chemistry and Chemical Engineering2016 - 2018A New Experimental Platform to Analyze anti-gB Antibodies in Human B CellsFehr, AnthonyKU Molecular Bioscience2020 - 2021Deciphering the Distinct Roles of Macrodomain ADP-Ribose Binding and Hydrolysis in Coronavirus ReplicationGovind, RevathiKSU Division of Biology2016 - 2018Curtailing Clostridium Difficile VirulenceHardwidge, Philip R.KSU Depts. of Diagnostic Medicine and Pathobiology2019 - 2020Bacterial glycosyltransferase inhibitors as anti-virulence compoundsHutchison, JustinKU Civil, Environmental and Architectural Engineering2020 - 2021Phage-protein based removal of pathogenic non-tuberculous Mycobacterium from drinking waterKim, HyunjoonKU Pharmaceutical Chemistry2022 - 2023Discovery of oral vaccine adjuvant to enhance mucosal immunity for treatment of GI infectious diseaseSathyamoorthi, ShyamKU Medicinal Chemistry2020 - 2021First Enantioselective Syntheses of Bactobolins A, B, and Analogue AntiobioticsSiahaan, Teruna J.KU Pharmaceutical Chemistry2021 - 2023Discovery of Inhibitors for the SARS-CoV-2-Mpro Enzyme as Covid19 AntiviralsSlusky, Joanna S.G.KU Molecular Biosciences2022 - 2023Plugging Antibiotic Efflux with KlebC Fragments to Make Resistant Bacteria Vulnerable to AntibioticsWang, Michael ZhuoKU Pharmaceutical Chemistry2018 - 2019Identification of CYP5122A1 inhibitors as therapeutic agents for leishmaniasisZückert, WolframKUMC Microbiology, Molecular Genetics and Immunology2019 - 2020Small Molecule Inhibitors of Bacterial Surface Lipoprotein Secretion