Publications

Research publications acknowledging COBRE CBID grant funding (NIH P20GM113117)

How (and when) should I credit CBID CoBRE in my publications?

Research Publications

  1. Chilamari M, Immel J, Chen P-H, Alghafli B, Bloom, S. Flavin Metallaphotoredox Catalysis: Synergistic Synthesis in Water. ACS Catal. 2022, 12(7): 4175-4181. PMID: pending; PMCID: pending; NIHMS1815259.
  2. Henderson IM, Zeng F, Bhuiyan NH, Luo D, Martinez M, Smoake J, Bi F, Perera C, Johnson D, Prisinzano TE, Wang W, Uhl GR. Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development. Biochem Pharmacol. 2022 Jan;195:114868. Epub 2021 Dec 2. PMID: 34863978; PMCID: pending.
  3. Hutchison, JM, Zhengxi L, Chang C, Hiripitiyage Y, Wittman M, Romero A, Sturm BSM. Improving correlation of wastewater SARS-CoV-2 gene copy numbers with COVID-19 public health cases using readily available biomarkers. FEMS Microbes. 2022. PMID: pending; NIHMSID: NIHMS1792112.
  4. Ning K, Roy A, Cheng F, Xu P, Kleiboeker S, Escalante CR, Wang J, Qiu J. High-Throughput Screening Identifies Inhibitors for Parvovirus B19 Infection of Human Erythroid Progenitors. J Virol. 2022 Jan 26;96(2):e0132621. Epub 2021 Oct 20. PMID: 34669461; PMCID: PMC8791288
  5. Tetteh JT, Pham A, Peltier E, Hutchison JM, Barati Ghahfarokhi R. Predicting the electrokinetic properties on an outcrop and reservoir composite carbonate surfaces in modified salinity brines using extended surface complexation models. Fuel. February 2022 309:122078. PMID: pending; NIHMSID: NIHMS1792140.
  6. Upadhyay SP, Singh V, Sharma R, Zhou Z, Thapa P, Johnson DK, Keightley A, Chen M, Suo W, Sharma M. Influence of ligand geometry on cholinesterase enzyme - A comparison of 1-isoindolinone based structural analog with Donepezil. Journal of Molecular Structure. 2022 Jan 9; 1247:131385. PMID: 34776532; PMCID: PMC8589283.
  1. Abisado RG, Kimbrough JH, McKee BM, Craddock VD, Smalley NE, Dandekar AA, Chandler JR. Tobramycin adaptation enhances policing of social cheaters in Pseudomonas aeruginosa. Appl Environ Microbiol AEM. 2021 87(12):e0002921. PMID: 3383701; PMCID: pending.
  2. Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. J Virol. 2021 Jan 13;95(3):e01969-20. PMID: 33158944; PMCID: PMC7925111. 
  3. Budiardjo SJ, Ikujuni AP, Firlar E, Cordova A, Kaelber JT, Slusky JSG. High-Yield Preparation of Outer Membrane Protein Efflux Pumps byin Vitro Refolding is Concentration Dependent. J Membr Biol. Feb 2021, 254(1):41-50. PMID: 33462665. PMC pending. 
  4. Chitsike L, Yuan CH, Roy A, Boyle K, Duerksen-Hughes PJ. A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV+ head and neck squamous cell carcinomas. Oncotarget. 2021 Mar 16;12(6):549-561. PMID: 33796223; PMCID: PMC798482; doi: 10.18632/oncotarget.27908. eCollection 2021 Mar 16. 7. 
  5. Dhokale RA, Seidl FJ, Shinde AH, Mague JT, Sathyamoorthi S. Tethered Silanoxyiodination of Alkenes. J Org Chem. 2021 Jul 2;86(13):9233-9243. PMID: 34128664; NIHMS: 1793437. Epub 2021 Jun 15.
  6. Dhokale RA, Seidl FJ, Sathyamoorthi S. A Formal Rearrangement of Allylic Silanols. Molecules. 2021 Jul 23;26(13):3829. PMID: 34201779; PMCID: PMC8270268.
  7. Dimond ZE, Suchland RJ, Baid S, LaBrie SD, Soules KR, Stanley K, Carrell S, Kwong F, Wang Y, Rockey DD, Hybiske K, Hefty PS. Inter-species lateral gene transfer focused on the Chlamydia plasticy zone identifies loci associated with immediate cytotoxicty and inclusion stability. Mol Micro. 2021 116(6):1433-1448. Epub 2021 Nov 16.PMID 34738268;  PMCID: pending. 
  8. Dogrammatzis C, Saleh S, Deighan C, Kalamvoki M. Diverse Populations of Extracellular Vesicles with Opposite Functions during Herpes Simplex Virus 1 Infection. J Virol. 2021 Feb 24;95(6):e02357-20. PMID: 33361424; PMCID: PMC8094966
  9. Fahad AS, Timm MR, Madan B, Burgomaster KE, Dowd KA, Normandin E, Gutiérrez-González MF, Pennington JM, De Souza MO, Henry AR, Laboune F, Wang L, Ambrozak DR, Gordon IJ, Douek DC, Ledgerwood JE, Graham BS, Castilho LR, Pierson TC, Mascola JR, DeKosky BJ.Functional Profiling of Antibody Immune Repertoirs in Convalescent Zika Virus Disease Patients. Frontiers in Immunology. Feb 24 2021, 12:615102. PMID:33732238; PMCID: PMC7959826.
  10. Farrell MP, Kurhade SE, Weiner JD, Gao FP. Functionalized High Mannose‐Specific Lectins for the Discovery of Type I Mannosidase Inhibitors. Angewandte Chemie. Mar 16 2021. PMID: 33728787. PMCID: pending. 
  11. Hutchison JM, Mayer B, Vega M, Chacha W, Zilles J. Making Waves: Biocatalysis and Biosorption: Opportunities and challenges associated with a new protein-based toolbox for water and wastewater treatment.Water Research X. August 2021, 12:100112. PMID:34409281; PMCID: PMC8361250.
  12. Ingham DJ, Blankenfeld BR, Chacko S, Perera C, Oakley BR, Gamblin TC. Fungally Derived Isoquinoline Demonstrates Inducer-Specific Tau Aggregation Inhibition. Biochemistry. 2021 Jun 1;60(21):1658-1669. Epub 2021 May 19. PMID: 34009955; PMCID: PMC8173610.
  13. Kazmierski WM, Miriyala N, Johnson DK, and Baskaran S. The Discovery of Conformationally Constrained Bicyclic Peptidomimetics as Potent Hepatitis C NS5A Inhibitors. ACS Med. Chem. Lett.  2021 Sept 15; 12(11): 1649–1655. PMID: 34790290; PMCID: PMC8591741.
  14. Kolluru S, Singh M, Gaskins B, and Boskovic Z. Nickel-catalyzed annulations of ortho-haloarylimines. ACS catalysis.2021 Aug 20;11(16):10351-10361. PMID: 34777907; PMCID: pending.
  15. Lockbaum GJ, Reyes AC, Lee JM, Tilvawala R, Nalivaika EA, Ali A, Kurt Yilmaz N, Thompson PR, Schiffer CA. Crystal Structure SARS-CoV-2 main protease in complex with the non-covalent inhibitor ML188. Viruses. 2021, 13(2): 174. PMID:33503819. PMCID: PMC7911568.
  16. Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, Filippov DV, Gagné JP, Grimaldi G, Guettler S, Hoch NC, Hottiger MO, Korn P, Kraus WL, Ladurner A, Lehtiö L, Leung AKL, Lord CJ, Mangerich A, Matic I, Matthews J, Moldovan GL, Moss J, Natoli G, Nielsen ML, Niepel M, Nolte F, Pascal J, Paschal BM, Pawłowski K, Poirier GG, Smith S, Timinszky G, Wang ZQ, Yélamos J, Yu X, Zaja R, Ziegler M. ADP-ribosyltransferases, an update on function and nomenclature. FEBS J. 2021 Jul 29. PMID: 34323016; PMCID pending. Online ahead of print.
  17. Ly CY, Yu C, McDonald P, Roy A, Johnson DK, Davido DJ. Simple and Rapid High-Throughput Assay to Identify HSV-1 ICP0 Transactivation Inhibitors. Antiviral Res. 2021 Oct;194:105160. PMID:34384824; PMCID: pending; doi: 10.1016/j.antiviral.2021.105160. Epub 2021 Aug 9.
  18. Madan B, Zhang B, Xu K, Chao CW, O'Dell S, Wolfe JR, Chuang GY, Fahad AS, Geng H, Kong R, Louder MK, Nguyen TD, Rawi R, Schön A, Sheng Z, Nimrania R, Wang Y, Zhou T, Lin BC, Doria-Rose NA, Shapiro L, Kwong PD, DeKosky BJ. Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2011653118. PMID: 33649208; PMCID: PMC7958426.
  19. Mintoo M, Chakravarty A, and Tilvawala R.* N-Terminomics Strategies for Protease Substrates Profiling. Molecules.2021 Aug 3;26(15):4699. PMID: 34361849; PMCID: PMC8348681. *Corresponding Author.
  20. Ning K, Roy A, Cheng F, Xu P, Kleiboeker S, Escalante CR, Wang J, Qiu J. High throughput screening identifies inhibitors for parvovirus B19 infection of human erythroid progenitor cells. J Virol. 2021 Oct 20;:JVI0132621. PMID: 34669461; PMCID: pending. [Epub ahead of print] 
  21. Provance OK, Geanes ES, Lui AJ, Roy A, Holloran SM, Gunewardena S, Hagan CR, Weir S, Lewis-Wambi J. Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression. Cancer Lett. 2021 Aug 28;514:12-29. Epub 2021 May 20. PMID: 34022283; PMCID: PMC8221017.
  22. Ross, P, Farrell, MP. The Road to Structurally Defined b-Glucans, The Chemical Record. 2021 Nov;21(11):3178-3193. PMID: 34010496; NIHMS: 1792138.
  23. Roy A. High Throughput Screening. Encyclopedia of Molecular Pharmacology 3rd ed. 2021 Edition by Stefan Offermanns (Editor), Walter Rosenthal (Editor Springer; 3rd ed. 2021 edition (December 2, 2021), ISBN-13: 978-3030574000.
  24. Shinde AH, Thomas AA, Mague JT, Sathyamoorthi S. Highly Regio- and Diastereoselective Tethered Aza-Wacker Cyclizations of Alkenyl Phosphoramidates. J Org Chem. 2021 Nov 5;86(21):14732-14758. PMID: 34665630; PMCID pending. Epub 2021 Oct 19.
  25. Sun B, Tomita B, Salinger A, Tilvawala R, Li L, Hakami H, Liu T, Tsoyi K, Rosas IO, Reinhardt DP, Thompson PR, Ho IC. PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis. Matrix Biol. 2021 Aug;102:70-84. PMID: 34274450; PMC8502204.
  26. Tilvawala R, Nemmara VV, Salinger AJ, Sorvillo N, Wagner DD and Thompson PR. The Role of SERPIN Citrullination in Thrombosis. Cell Chem Bio. 2021 Dec 16;28(12):1728-1739.e5. PMID: 34352225; PMC8688209.
  27. Voth LS, O'Connor JJ, Kerr CM, Doerger E, Schwarting N, Sperstad P, Johnson DK, Fehr AR. Unique mutations in the MHV macrodomain differentially attenuate virus replication, indicating multiple roles for the macrodomain in coronavirus replication. J Virol2021 Jul 12;95(15):e0076621. PMID: 34011547; PMCID pending. Epub 2021 Jul 12. 
  28. Voth LS, O'Connor JJ, Kerr CM, Doerger E, Schwarting N, Sperstad P, Johnson DK, Fehr AR. An MHV macrodomain mutant predicted to lack ADP-ribose binding activity is severely attenuated, indicating multiple roles for the macrodomain in coronavirus replication. bioRxiv. 2021 Mar31:2021.03.30.437796. PMID: 33821264; PMCID: PMC8020964. Preprint.
  29. Yang Y, Borel T, de Azambuja F, Johnson DK, Sorrentino JP, Udokwu C, Davis I, Liu A, Altman RA. Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway. J Med Chem. Jan 14 2021, 64(1):797-811. PMID:33369426; PMC pending.
  30. Zhu C, El Qaidi S, McDonald P, Roy A, Hardwidge PR. YM155 inhibits NleB and SseK arginine glycosyltransferase activity. Pathogens. Feb 23 2021, 10(2):253. PMID: 33672424; PMCID: PMC7926936.
  1. Alhammad YMO, Fehr AR. The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation. Viruses. 2020 Apr; 12(4): 384. Published online 2020 Mar 31. PMID: 32244383; PMCID: PMC7232374.
  2. Alhammad YMO, Kashipathy MM, Roy A, Gagne JP, Nonfoux L, McDonald P, Gao P, Battaile KP, Johnson DK, Poirier GG, Lovell S, Fehr A. The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase. bioRxiv. Preprint. 2020 May 12 [revised 2020 Jun 1]. PMID: 32511412; PMCID: PMC7263559. 
  3. Bawa S, Gameros S, Baumann K, Brooks DS, Kollhoff JA, Zolkiewski M, David Re Cecconi A, Panini N, Russo M, Piccirillo R, Johnson DK, Kashipathy MM, Battaile KP, Lovell S, Bouyain SEA, Kawakami J, Geisbrecht ER. Costameric integrin and Sarcoglycan protein levels are altered in a Drosophila model for Limb Girdle Muscular Dystrophy type 2H.Mol Biol Cell. Dec 9, 2020, Epub ahead of print. PMID:33296226. PMCID: PMC8098830. 
  4. Benomar S, Lansdon P, Bender AM, Peterson BR, Chandler JR, Ackley BD. The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen. PLoS Pathog. 2020 Jan;16(1):e1008134. eCollection 2020 Jan. PMID: 31917826; PMCID: PMC6952083.
  5. Chilamari M, Immel J, Bloom S.General Access to C-Centered Radicals: Combining a Bioinspired Photocatalyst with Boronic Acids in Aqueous Media. ACS Catal. 2020 10(21):12727–12737. PMID:  in process; PMCID in process.
  6. Christopher MA, Johnson SN, Griffin JD, Berkland CJ. Autoantigen Tetramer Silences Autoreactive B Cell Populations. Mol Pharm. 2020 Nov 2;17(11):4201-4211. PMID: 32903002; PMCID: PMC7606775. Epub 2020 Oct 6.
  7. DeMars Z, Singh VK, Bose JL. Exogenous fatty acids remodel Staphylococcus aureus lipid composition through fatty acid kinase. J Bacteriol. 2020 Jun 25;202(14):e00128-20. PMID: 32366591; PMCID: PMC7317038.
  8. Dhungel BA, Govind R. Spo0A Suppresses sin Locus Expression in Clostridioides difficile. mSphere. 2020 Nov 4;5(6):e00963-20. PMID: 33148827; PMCID: PMC7643835.
  9. Dimond ZE, Hefty PS. Comprehensive genome analysis and comparisons of the swine pathogen, Chlamydia suis reveals unique ORFs and candidate host-specificity factors. [published online ahead of print, 2020 Jul 8]. Pathog Dis. 2020;ftaa035. PMID: 32639528; PMCID: 7948067.
  10. Dogrammatzis C, Waisner H, Kalamvoki M. "Non-Essential" Proteins of HSV-1 with Essential Roles In Vivo: A Comprehensive Review. Viruses. 2020 Dec 23;13(1):17. PMID: 33374862; PMCID: PMC7824580.
  11. Fehr AR. Bacterial Artificial Chromosome-Based Lambda Red Recombination with the I-SceI Homing Endonuclease for Genetic Alteration of MERS-CoV. MERS Coronavirus. 2020; 2099: 53–68. Published online 2019 Sep 14. PMID: 31883087; PMCID: PMC7121842.
  12. Fehr AR, Singh SA, Kerr CM, Mukai S, Higashi H, Aikawa M. The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions. Genes Dev. 2020 Mar 1;34(5-6):341-359. PMID: 32029454; PMCID: PMC7050484.
  13. Greenberg EP, Chandler JR and Seyedsayamdost M. The chemistry and biology of bactobolin: A 10-year collaboration with natural product chemist extraordinaire Jon Clardy. Journal of Natural Products  2020 83(3):738. PMID: 32105069: PMCID: PMC8118907. 
  14. Grunewald ME, Shaban MG, Mackin SR, Fehr AR, Perlman S. Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression. J Virol. 2020 Jan 17;94(3):e01743-19. PMID: 31694960; PMCID: PMC7000979.
  15. Heer CD, Voth LS, Sanderson DJ, Alhammad YMO, Schmidt MS, Trammell SAJ, Perlman S, Cohen MS, Fehr AR, Brenner C. Coronavirus and PARP expression dysregulate the NAD Metabolome: a potentially actionable component of innate immunity. October 2020 PMID: 32511303; PMCID: PMC7217258. 
  16. Jin W, Madan B, Mussman BK, Hailemariam AT, Fahad AS, Wolfe JR, Kwon YD, Zhang B, Shapiro L, Kwong PD, DeKosky BJ.The covalent SNAP tag for protein display quantification and low-pH protein engineering. J Biotechnol. 2020 Aug 20;320:50-56. PMID: 32561362; PMCID: PMC7434562. Epub 2020 Jun 16.
  17. Joseph AM, Pohl AE, Ball TJ, Abram TG, Johnson DK, Geisbrecht BV, Shames SR. The Legionella pneumophila Metaeffector Lpg2505 (MesI) Regulates SidI-Mediated Translation Inhibition and Novel Glycosyl Hydrolase Activity. Infect Immun. 2020 Apr 20;88(5). PMID: 32122942; PMCID: PMC7171249. 
  18. Klaus JR, Coulon PML, Koirala P, Seyedsayamdost MR, Deziel E, Chandler JR. Secondary metabolites from the Burkholderia pseudomallei complex: structure, ecology and evolution. Review. Journal of Industrial Microbiology and Biotechnology, October 14, 2020. PMID: 33052546; PMCID: PMC7746414.
  19. Klaus JR, Majerczyk C, Moon S, Eppler NA, Smith S, Tuma E, Groleau M-C, Asfahl KL, Smalley NE, Hayden HS, Piochon M, Ball P, Dandekar AA, Gauthier C, Deziel E, and Chandler JR. Burkholderia thailandensis methylated hydroxy-aklylquinolines: biosynthesis and antimicrobial activity in co-cultures. Applied and Environmental Microbiology, October 2020. AEM.01452-20. PMID:33008823. PMCID: PMC7688213.
  20. Kurland M, O'Meara B, Tucker DK, Ackley BD. The Hox Gene egl-5 Acts as a Terminal Selector for VD13 Development via Wnt Signaling. J Dev Biol. 2020 Mar 3;8(1):5. PMID: 32138237; PMCID: PMC7151087.
  21. Lin Y, Qiao W, Yang Z. Ribosome profiling of vaccinia virus-infected cells. Vaccinia Virus: Methods and Protocols. Methods in Molecular Biology.  Book chapter. In press.
  22. Muthuramalingam M, Whittier SK, Lovell S, Battaile KP, Tachiyama S, Johnson DK, Picking WL, Picking WD. The Structures of SctK and SctD from Pseudomonas aeruginosa Reveal the Interface of the Type III Secretion System Basal Body and Sorting Platform. J Mol Biol. 2020 Dec 4;432(24):166693. PMID: 33122003; PMCID pending. 
  23. Peng C, Zhou Y, Cao S, Pant A, Campos Guerrero ML, McDonald P, Roy A, Yang Z. Identification of Vaccinia Virus Inhibitors and Cellular Functions Necessary for Efficient Viral Replication by Screening Bioactives and FDA-Approved Drugs.Vaccines (Basel). 2020 Jul 21;8(3): E401. PMID: 32708182; PMCID 7564539; doi: 10.3390/vaccines8030401. 
  24. Ridder MJ, Daly SM, Triplett KD, Seawell NA, Hall PR, Bose JL. Staphylococcus aureus fatty acid kinase FakA modulates pathogenesis during skin infection via proteases. Infect Immun. 2020 Jul 21;88(8):e00163-20. PMID: 32513856; PMCID: PMC7375762.
  25. Shinde AH, Sathyamoorthi S. Oxidative Cyclization of Sulfamates onto Pendant Alkenes. Org. Lett. 2020, 22, 896-901. PMID: 31927967. no PMCID found
  26. Shinde AH, Sathyamoorthi S. Tethered Silanoxymercuration of Allylic Alcohols. Org Lett. 2020 Nov 6;22(21):8665-8669. PMID: 33095992. Epub 2020 Oct 23. no PMCID found
  27. Song JY, Griffin JD, Larson NR, Christopher MA, Middaugh CR, Berkland CJ. Synthetic Cationic Autoantigen Mimics Glatiramer Acetate Persistence at the Site of Injection and Is Efficacious Against Experimental Autoimmune Encephalomyelitis. Front Immunol. 2021 Jan 18;11:603029. PMID: 33537031; PMCID: PMC7848024. eCollection 2020.
  28. Soules KR, Dmitriev A, LaBrie SD, Dimond ZE, May BH, Johnson DK, Zhang Y, Battaile KP, Lovell S, Hefty PS. Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulation. Mol Microbiol. 2020 Jan;113(1):68-88. PMID: 31637787; PMCID: PMC7007330.
  29. Soules KR, LaBrie SD, May BH, Hefty PS. Sigma 54-Regulated Transcription Is Associated with Membrane Reorganization and Type III Secretion Effectors during Conversion to Infectious Forms of Chlamydia trachomatis. mBio. 2020 Sep 8;11(5):e01725-20. PMID: 32900805; PMCID 748206. 
  30. Thomas AA, Nagamalla S, Sathyamoorthi S. Salient features of the aza-Wacker cyclization reaction. Chem Sci. 2020 Aug 21;11(31):8073-8088. PMID: 34123081; PMCID: 8163389.
  31. Yang Z, Mattingly BC, Hall DH, Ackley BD, Buechner M. Terminal Web and Vesicle Trafficking Proteins Mediate Nematode Single-Cell Tubulogenesis. J Cell Biology2020 Nov 2;219(11):e202003152. PMID: 32860501; PMCID: PMC7594493.
     
  1. Austin CM, Garabaglu S, Krute CN, Ridder MJ, Seawell NA, Markiewicz MA, Boyd JM, Bose JL. Contribution of YjbIH to virulence factor expression and host colonization in Staphylococcus aureus. Infect Immun. 2019 May 21;87(6):e00155-19. Print 2019 Jun. PMID: 30885928; PMCID: PMC6529663.
  2. Cao S, Lin Y, Yang Z. Vaccinia Virus Transcriptome Analysis by RNA Sequencing. Methods Mol Biol. 2019;2023:157-170. PMID: 31240677; PMCID: pending. 
  3. Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray Jr. PB, Meyerholz DK, Perlman S. IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. J Clin Invest. 2019 Sep 3;129(9): 3625-3639. PMID: 31355779; PMCID: PMC6715373.
  4. Ciftci Y, Girinathan BP, Dhungel BA, Hasan MK, Govind R. Clostridioides difficile SinR' regulates toxin, sporulation and motility through protein-protein interaction with SinR. Anaerobe. 2019 Oct;59:1-7. PMID: 31077800; PMCID: PMC6785386. Epub 2019 May 8.
  5. Deschamps T, Waisner H, Dogrammatzis C, Roy A, Chacko S, Perera C, Prisinzano TE, Kalamvoki M. Discovery of Small-Molecule Inhibitors Targeting the E3 Ubiquitin Ligase Activity of the Herpes Simplex Virus 1 ICP0 Protein Using an In Vitro High-Throughput Screening Assay. J Virol.2019 Jul 1;93(13). PMID: 30996104; PMCID: PMC6580980.
  6. Dogrammatzis C, Deschamps T, Kalamvoki M. Biogenesis of Extracellular Vesicles during Herpes Simplex Virus 1 Infection: Role of the CD63 Tetraspanin. J Virol. 2019 Jan 15;93(2) : e01850-18. PMID: 30355691; PMCID: PMC6321934.
  7. Grunewald ME, Chen Y, Kuny C, Maejima T, Lease R, Ferraris D, Aikawa M, Sullivan CS, Perlman S, Fehr AR. 2019. The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression. PLoS Pathog. 2019 May 16;15(5):e1007756. PMID: 31095648; PMCID: PMC6521996.
  8. LaBrie SD, Dimond ZE, Harrison KS, Baid S, Wickstrum J, Suchland RJ, Hefty PS. Transposon Mutagenesis in Chlamydia trachomatis Identifies CT339 as a ComEC Homolog Important for DNA Uptake and Lateral GeneTransfer. mBio. 2019 Aug 6;10(4). PMID: 31387908; PMCID: PMC6686042.
  9. Lagerman CE, López Acevedo SN, Fahad AS, Hailemariam AT, Madan B, DeKosky BJ. Ultrasonically-guided flow focusing generates precise emulsion droplets for high-throughput single cell analyses. J Biosci Bioeng. 2019 Aug;128(2):226-233. PMID: 30904454; PMCID: PMC6688500. Epub 2019 Mar 20. 
  10. Lin Y, Yang Z, Qiao WT. Deciphering viral infections by ribosome profiling. Chinese J of Virology2019 35(6):984-990.  PMID: not found; PMCID: not found;
  11. Ngwaga T, Hydock AJ, Ganesan S, Shames SR. Potentiation of Cytokine-Mediated Restriction of Legionella Intracellular Replication by a Dot/Icm-Translocated Effector. J Bacteriol. 2019 Jun 21;201(14). pii: e00755-18. PMID: 31036725; PMCID: PMC6597390.
  12. Roy A, McDonald P, Timmermann BN, Gupta M, Chaguturu R. Bioactivity Profiling of Plant Biodiversity of Panama by High Throughput Screening. Nat Prod Commun. 2019 Jan; 14(1): 71–74. PMID: 31938081; PMCID: PMC6959481; doi: 10.1177/1934578X1901400119.
  13. Roy A. Challenges with risk mitigation in academic drug discovery: finding the best solution. Expert Opin Drug Discov. Feb 2019, 14(2):95-100. PMID: 30513005. PMC6467222.
  14. Waisner H, Kalamvoki M. The ICP0 Protein of Herpes Simplex Virus 1 (HSV-1) Downregulates Major Autophagy Adaptor Proteins Sequestosome 1 and Optineurin during the Early Stages of HSV-1 Infection. J Virol. 2019 Oct 15;93(21). pii: e01258-19. PMID: 31375597; PMCID: PMC6803258.
  1. Deschamps T, Kalamvoki M. Extracellular Vesicles Released by Herpes Simplex Virus 1-Infected Cells Block Virus Replication in Recipient Cells in a STING-Dependent Manner. J Virol. 2018 Sep 15; 92(18): e01102-18. PMID: 29976662; PMCID: PMC6146713.
  2. El Qaidi S, Zhu C, McDonald P, Roy A, Maity PK, Rane D, Perera C, Hardwidge PR. High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors. Front Cell Infect Microbiol. 2018;8:435. eCollection 2018. PMID: 30619781; PMCID: PMC6305410.
  3. Girinathan BP, Ou Junjun, Durpuy B and Govind R. Pleiotropic roles of Clostridium difficile sin locus. PLoS Pathogens  2018 Mar 12;14(3):e1006940. PMID: 29529083; PMCID: PMC5864091.
  4. Kfoury N, Sun T, Yu K, Rockwell N, Tinkum KL, Qi Z, Warrington NM, McDonald P, Roy A, Weir SJ, Mohila CA, Deneen B, Rubin JB. Cooperative p16 and p21 action protects female astrocytes from transformation. Acta Neuropathol Commun. 2018 Feb 20;6(1):12. PMID: 29458417; PMCID: PMC5819173.
  5. Kivell BM, Paton KF, Kumar N, Morani AS, Culverhouse A, Shepherd A, Welsh SA, Biggerstaff A, Crowley RS, Prisinzano TE. Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents. Molecules. 2018 Oct; 23(10): 2602. PMID: 30314288; PMCID: PMC6222496.
  6. Klaus JR, Deay J, Neuenswander B, Hursh W, Gao Z, Bouddhara T, Williams TD, Douglas J, Monize K, Martins P, Majerczyk C, Seyedsayamdost MR, Peterson BR, Rivera M, Chandler JR. Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing. J Bacteriol. 2018 Jun 25;200(14). PMID: 29735757; PMCID: PMC6018353.
  7. Ngwaga T, Hydock AJ, Ganesan S, Shames, SR. The Dot/Icm-translocated effector LegC4 potentiates cytokine-mediated restriction of Legionella within accidental hosts. bioRxiv 493197 (preprint), posted December 11, 2018
  8. Parrales A, McDonald P, Ottomeyer M, Roy A, Shoenen FJ, Broward M, Bruns T, Thamm DH, Weir SJ, Neville KA, Iwakuma T, Fulbright JM. Comparative oncology approach to drug repurposing in osteosarcoma. PLoS One. 2018 Mar 26;13(3)e0194224. PMID: 29579058; PMCID: PMC5868798.
  9. Polpitiya Arachchige S, Henke W, Pramanik A, Kalamvoki M, Stephens EB. Analysis of Select Herpes Simplex Virus 1 (HSV-1) Proteins for Restriction of Human Immunodeficiency Virus Type 1 (HIV-1): HSV-1 gM Protein Potently Restricts HIV-1 by Preventing Intracellular Transport and Processing of Env gp160. J Virol. 2018 Jan 15; 92(2): e01476-17. PMID: 29093081; PMCID: PMC5752927.
  10. Quaidi SE, Zhu C, McDonald P , Roy A, Maity PK, Rane D, Perera C, Hardwidge PR. High-Throughput Screening for Bacterial Glycosyltransferase Inhibitors. Front Cell Infect Microbiol. 2018 Dec 18;8:435. PMID: 30619781; PMCID: PMC6305410. eCollection 2018.
  11. Roy A. Early Probe and Drug Discovery in Academia: A Minireview. High Throughput. 2018 Feb 9;7(1):4. PMID: 29485615; PMCID: PMC5876530.
  12. Tai S, Vasiljevik T, Sherwood AM, Eddington S, Wilson CD, Prisinzano TE, Fantegrossi WE. Assessment of rimonabant-like adverse effects of purported CB1R neutral antagonist / CB2R agonist aminoalkylindole derivatives in mice. Drug Alcohol Depend.2018 Nov 1;192:285-293. PMID: 30300803; PMCID: PMC6475911.
  13. Vaidya A, Roy A, Chaguturu R. How to rekindle drug discovery process through integrative therapeutic targeting?Expert Opin Drug Discov. 2018 Oct;13(10):893-898. PMID: 30146919; PMCID: PMC6436386.
     
  1. Cao S, Dhungel P, Yang Z. Going against the Tide: Selective Cellular Protein Synthesis during Virally Induced Host Shutoff. J Virol. 2017 Aug 10;91(17). PMID: 28637757; PMCID: PMC5553178.
  2. Cao S, Realegeno S, Pant A, Satheshkumar PS, Yang Z. Suppression of poxvirus replication by resveratrol. Front Microbiol. 2017 Nov 17;8:2196. PMID: 29204136; PMCID: PMC5698801.
  3. Dai A, Cao S, Dhungel P, Luan Y, Liu Y, Xie Z, Yang, Z. Ribosome Profiling Reveals Translational Upregulation of Cellular Oxidative Phosphorylation mRNAs during Vaccinia Virus-Induced Host Shutoff. Journal of Virology Mar 2017, 14:91(5):pii:JVI.00071-17. PMID: 28003488; PMCID: PMC5309933. 
  4. Deschamps T, Kalamvoki M. Impaired STING Pathway in Human Osteosarcoma U2OS Cells Contributes to the Growth of ICP0-Null Mutant Herpes Simplex Virus. Journal of Virology Apr 2017, 13:91(9):pii:e00006-17. PMID: 28179534. PMC5391473.
  5. Deschamps T, Dogrammatzis C, Mullick R, Kalamvoki M. Cbl E3 Ligase Mediates the Removal of Nectin-1 from the Surface of Herpes Simplex Virus 1-Infected Cells.  J Virol. 2017 May 26;91(12). PMID: 28381567; PMCID: PMC5446655.
  6. Deschamps T, Kalamvoki M. Evasion of the STING DNA-Sensing Pathway by VP11/12 of Herpes Simplex Virus 1. J Virol. 2017 Jul 27;91(16). PMID: 28592536; PMCID: PMC5533902.
  7. Dhungel P, Cao S, Yang Z.The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation. PLoS Pathog. 2017 Aug 30;13(8):e1006602. PMID: 28854224; PMCID: PMC5595341.
  8. Girinathan BP, Monot M, Boyle D, McAllister KN, Sorg JA, Dupuy B, Govind R. Effect of tcdR mutation on sporulation in the epidemic Clostridium difficile strain R20291. mSphere2017 Feb 15;2(1). PMID: 28217744; PMCID: PMC531115.
  9. Komiya T, Yamamoto S, Roy A, McDonald P, Perez RP. Drug screening to target nuclear orphan receptor NR4A2 for cancer therapeutics. Transl Lung Cancer Res. 2017 Oct;6(5):600-610. PMID: 29114475; PMCID: PMC5653521.
  10. Roy A, Mir MA. Development of High-Throughput Screening Assay for Antihantaviral Therapeutics. SLAS Discov. 2017 Jul;22(6):767-774. PMID: 28340538; PMCID: PMC5854180.
  1. Budiardjo SJ, Licknack TJ, Cory MB, Kapros D, Roy A, Lovell S, Douglas J, Karanicolas J. Full and Partial Agonism of a Designed Enzyme Switch. ACS Synthetic Biology Dec 2016, 16:5(12):1475-84. PMID: 27389009; PMCID: PMC5161622.
  2. Gowthaman R, Miller SA, Rogers S, Khowsathit J, Lan L, Bai N, Johnson DK, Liu C, Xu L, Anbanandam A, Aubé J, Roy A, Karanicolas J. DARC: Mapping Surface Topography by Ray-Casting for Effective Virtual Screening at Protein Interaction Sites. Journal of Medicinal Chemistry May 2016, 12:59(9):4152-70. PMID: 26126123; PMCID: PMC4707132.
  3. Kim S, Patel DS, Park S, Slusky J, Klauda JB, Widmalm G, Im W. Bilayer Properties of Lipid A from Various Gram-Negative Bacteria. Biophysical Journal Oct 2016, 18:111(8):1750-60. PMID: 27760361; PMCID: PMC5071556.
  4. Lee MM, Peterson BR. Quantification of Small Molecule-Protein Interactions using FRET between Tryptophan and the Pacific Blue Fluorophore. ACS Omega Dec 2016, 31:1(6):1266-76. PMID: 28058293; PMCID: PMC5204206.
  5. Meneely KM, Ronnebaum TA, Riley AP, Prisinzano TE, Lamb AL. Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis. Biochemistry Sept. 27 2016, pp.5423-33. PMID: 27601130; PMCID: PMC5046821.
  6. Parrales A, Ranjan A, Iyer SV, Padhye S, Weir SJ, Roy A, Iwakuma T. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nature Cell Biology Nov 2016, 18(11):1233-1243. PMID: 27775703; PMCID: PMC5340314.
  7. Phaniraj S, Gao Z, Rane D, Peterson BR. Hydrophobic resorufamine derivatives: potent and selective red fluorescent probes of the endoplasmic reticulum of mammalian cells. Dyes and pigments: an international journal Dec 2016, 135:127-33. PMID: 27765999; PMCID: PMC5066811.
  8. Polireddy K, Dong R, McDonald PR, Wang T, Luke B, Chen P, Broward M, Roy A, Chen Q. Targeting Epithelial-Mesenchymal Transition for Identification of Inhibitors for Pancreatic Cancer Cell Invasion and Tumor Spheres Formation. PLoS one Oct 2016, 20:11(10):e0164811. PMID: 27764163; PMCID: PMC5072586.
  9. Roy A, Patwardhan B, Chaguturu R. Reigniting pharmaceutical innovation through holistic drug targeting. Drug Discovery World Summer 2016, pp.45-55.
  10. Salim NN, Ganaie SS, Roy A, Jeeva S, Mir MA. Targeting a Novel RNA-Protein Interaction for Therapeutic Intervention of Hantavirus Disease. Journal of Biological Chemistry Nov 2016, 18:291(47):24702-14. PMID: 27733686; PMCID: PMC5114419.
  11. Slusky JS. Outer membrane protein design. Current Opinion in Structural Biology Nov 2016, 25:45:45-52. PMID: 27894013; PMCID: PMC5445000.
  12. Valasani KR, Sun Q, Fang D, Zhang Z, Yu Q, Guo Y, Li J, Roy A, ShiDu Yan S. Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction. ACS Medicinal Chemistry Letters Jan 2016, 6:7(3):294-9. PMID: 26985318; PMCID: PMC4789676.